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ELK Biotechnology

SKU:ES2397

GAP1-InsP4 BP Rabbit Polyclonal Antibody

GAP1-InsP4 BP Rabbit Polyclonal Antibody

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GAP1-InsP4 BP Rabbit Polyclonal Antibody

Overview

Product name: GAP1-InsP4 BP rabbit pAb
Alternative Names: RASA3; Ras GTPase-activating protein 3; GAP1(IP4BP); Ins P4-binding protein
Applications: WB;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human RASA3. AA range:247-296
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 95kD
GeneID(Human): 22821
Human Swiss-Prot No: Q14644
Cellular localization: Cell membrane.
Background: This gene encodes a protein that binds inositol 1,3,4,5-tetrakisphosphate and stimulates the GTPase activity of Ras p21. This protein functions as a negative regulator of the Ras signalling pathway. It is localized to the cell membrane via a pleckstrin homology (PH) domain in the C-terminal region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
Species Reactivity: Human;Mouse;Rat
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