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ELK Biotechnology
SKU:ES2372
Frizzled-3 Rabbit Polyclonal Antibody
Frizzled-3 Rabbit Polyclonal Antibody
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Frizzled-3 Rabbit Polyclonal Antibody
Overview
| Product name: | Frizzled-3 rabbit pAb |
| Alternative Names: | FZD3; Frizzled-3; Fz-3; hFz3 |
| Applications: | WB;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human FZD3. AA range:141-190 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 76kD |
| GeneID(Human): | 7976 |
| Human Swiss-Prot No: | Q9NPG1 |
| Cellular localization: | Membrane; Multi-pass membrane protein. Cell membrane ; Multi-pass membrane protein . Cell surface . Apical cell membrane ; Multi-pass membrane protein. Colocalizes with FZD6 at the apical face of the cell (By similarity). . |
| Background: | frizzled class receptor 3(FZD3) Homo sapiens This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. This gene is a susceptibility locus for schizophrenia. [provided by RefSeq, Dec 2010], |
| Species Reactivity: | Human;Mouse |
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Western Blot analysis of various cells using Frizzled-3 Polyclonal Antibody -
Western Blot analysis of RAW264.7 cells using Frizzled-3 Polyclonal Antibody -
Immunofluorescence analysis of COS7 cells, using FZD3 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from A549 and RAW264.7 cells, using FZD3 Antibody. The lane on the right is blocked with the synthesized peptide.
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