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ELK Biotechnology
SKU:ES2367
FOXO4 Rabbit Polyclonal Antibody
FOXO4 Rabbit Polyclonal Antibody
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$248.00 USD
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FOXO4 Rabbit Polyclonal Antibody
Overview
| Product name: | FoxO4 rabbit pAb |
| Alternative Names: | FOXO4; AFX; AFX1; MLLT7; Forkhead box protein O4; Fork head domain transcription factor AFX1 |
| Applications: | WB;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human FOXO4. AA range:417-466 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 55kD |
| GeneID(Human): | 4303 |
| Human Swiss-Prot No: | P98177 |
| Cellular localization: | Cytoplasm. Nucleus. When phosphorylated, translocated from nucleus to cytoplasm. Dephosphorylation triggers nuclear translocation. Monoubiquitination increases nuclear localization. When deubiquitinated, translocated from nucleus to cytoplasm. |
| Background: | This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010], |
| Species Reactivity: | Human;Mouse;Monkey |
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Western Blot analysis of various cells using FoxO4 Polyclonal Antibody -
Immunofluorescence analysis of HeLa cells, using FOXO4 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from K562 cells, using FOXO4 Antibody. The lane on the right is blocked with the synthesized peptide.
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