ER81 Rabbit Polyclonal Antibody

Name: ER81 Rabbit Polyclonal Antibody
Brand: ELK Biotechnology
SKU: ES2286
Price: 248.0 USD
Availability: InStock

$248.00 USD

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Size 100ul

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ER81 Rabbit Polyclonal Antibody

Overview

Product name:	ER81 rabbit pAb
Alternative Names:	ETV1; ER81; ETS translocation variant 1; Ets-related protein 81
Applications:	WB;IHC;IF;ELISA
Recommended Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human ER81. AA range:10-59
Storage:	-20°C/1 year
Storage:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	60kD
GeneID（Human）:	2115
Human Swiss-Prot No:	P50549
Cellular localization:	Nucleus .
Background:	This gene encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5'-CGGA[AT]-3'. The protein encoded by this gene contains a conserved short acidic transactivation domain (TAD) in the N-terminal region, in addition to the ETS DNA-binding domain in the C-terminal region. This gene is involved in chromosomal translocations, which result in multiple fusion proteins including EWS-ETV1 in Ewing sarcoma and at least 10 ETV1 partners (see PMID: 19657377, Table 1) in prostate cancer. In addition to chromosomal rearrangement, this gene is overexpressed in prostate cancer, melanoma and gastrointestinal stromal tumor. Multiple alte
Species Reactivity:	Human;Mouse

Western Blot analysis of various cells using ER81 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Western Blot analysis of HuvEc cells using ER81 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Western blot analysis of lysates from HUVEC cells, treated with PMA 125ng/ml 30', using ER81 Antibody. The lane on the right is blocked with the synthesized peptide.
Western blot analysis of the lysates from HT-29 cells using ER81 antibody.

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ER81 Rabbit Polyclonal Antibody

ER81 Rabbit Polyclonal Antibody

Overview