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ELK Biotechnology
SKU:ES2261
Endo180 Rabbit Polyclonal Antibody
Endo180 Rabbit Polyclonal Antibody
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$248.00 USD
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Endo180 Rabbit Polyclonal Antibody
Overview
| Product name: | Endo180 rabbit pAb |
| Alternative Names: | MRC2; CLEC13E; ENDO180; KIAA0709; UPARAP; C-type mannose receptor 2; C-type lectin domain family 13 member E; Endocytic receptor 180; Macrophage mannose receptor 2; Urokinase-type plasminogen activator receptor-associated protein; UPAR-asso |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human MRC2. AA range:121-170 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 167kD |
| GeneID(Human): | 9902 |
| Human Swiss-Prot No: | Q9UBG0 |
| Cellular localization: | Membrane; Single-pass type I membrane protein. |
| Background: | mannose receptor C type 2(MRC2) Homo sapiens This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease. [provided by RefSeq, Feb 2012], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of various cells using Endo180 Polyclonal Antibody diluted at 1:1000 -
Immunofluorescence analysis of HepG2 cells, using MRC2 Antibody. The picture on the right is blocked with the synthesized peptide. -
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MRC2 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from 293 cells, using MRC2 Antibody. The lane on the right is blocked with the synthesized peptide.
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