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ELK Biotechnology

ES2204

DSCR 1 Rabbit Polyclonal Antibody

DSCR 1 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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DSCR 1 Rabbit Polyclonal Antibody

Overview

Product name: DSCR 1 rabbit pAb
Alternative Names: RCAN1; ADAPT78; CSP1; DSC1; DSCR1; Calcipressin-1; Adapt78; Down syndrome critical region protein 1; Myocyte-enriched calcineurin-interacting protein 1; MCIP1; Regulator of calcineurin 1
Applications: WB;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human RCAN1. AA range:201-250
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 22kD
GeneID（Human）: 1827
Human Swiss-Prot No: P53805
Cellular localization: intracellular,nucleus,cytoplasm,
Background: The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013],
Species Reactivity: Human;Mouse;Rat
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