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ELK Biotechnology
SKU:ES2191
Dok-2 Rabbit Polyclonal Antibody
Dok-2 Rabbit Polyclonal Antibody
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$248.00 USD
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Dok-2 Rabbit Polyclonal Antibody
Overview
| Product name: | Dok-2 rabbit pAb |
| Alternative Names: | DOK2; Docking protein 2; Downstream of tyrosine kinase 2; p56(dok-2) |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human p56 Dok-2. AA range:266-315 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 46kD |
| GeneID(Human): | 9046 |
| Human Swiss-Prot No: | O60496 |
| Cellular localization: | cytosol, |
| Background: | docking protein 2(DOK2) Homo sapiens The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse |
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Western Blot analysis of various cells using Dok-2 Polyclonal Antibody -
Western Blot analysis of COLO205 cells using Dok-2 Polyclonal Antibody -
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using p56 Dok-2 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from COLO205, using p56 Dok-2 Antibody. The lane on the right is blocked with the synthesized peptide.
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