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ELK Biotechnology

ES2181

DNA Ligase I Rabbit Polyclonal Antibody

DNA Ligase I Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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DNA Ligase I Rabbit Polyclonal Antibody

Overview

Product name: DNA Ligase I rabbit pAb
Alternative Names: LIG1; DNA ligase 1; DNA ligase I; Polydeoxyribonucleotide synthase [ATP] 1
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human DNL1. AA range:111-160
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 133kD
GeneID（Human）: 3978
Human Swiss-Prot No: P18858
Cellular localization: Nucleus.
Background: This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],
Species Reactivity: Human;Rat;Mouse;
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