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ELK Biotechnology

SKU:ES2126

Cytokeratin 16 Rabbit Polyclonal Antibody

Cytokeratin 16 Rabbit Polyclonal Antibody

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Cytokeratin 16 Rabbit Polyclonal Antibody

Overview

Product name: Cytokeratin 16 rabbit pAb
Alternative Names: KRT16; KRT16A; Keratin; type I cytoskeletal 16; Cytokeratin-16; CK-16; Keratin-16; K16
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Keratin 16. AA range:421-470
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 52kD
GeneID(Human): 3868
Human Swiss-Prot No: P08779
Cellular localization: nucleus,cytoskeleton,intermediate filament,extracellular exosome,
Background: The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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