The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described. [provided by RefSeq, Jul 2008],
Western Blot analysis of various cells using Cytokeratin 13 Polyclonal Antibody
Western Blot analysis of HepG2 cells using Cytokeratin 13 Polyclonal Antibody
Immunohistochemistry analysis of Cytokeratin 13 antibody in paraffin-embedded human heart tissue.
Western blot analysis of lysate from HepG2 cells, using Cytokeratin 13 antibody.