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ELK Biotechnology
SKU:ES2118
Cystatin A Rabbit Polyclonal Antibody
Cystatin A Rabbit Polyclonal Antibody
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Cystatin A Rabbit Polyclonal Antibody
Overview
| Product name: | Cystatin A rabbit pAb |
| Alternative Names: | CSTA; STF1; STFA; Cystatin-A; Cystatin-AS; Stefin-A |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Stefin A. AA range:49-98 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 11kD |
| GeneID(Human): | 1475 |
| Human Swiss-Prot No: | P01040 |
| Cellular localization: | Cytoplasm . |
| Background: | The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Rat;Mouse; |
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Western Blot analysis of various cells using Cystatin A Polyclonal Antibody -
Western Blot analysis of HT29 cells using Cystatin A Polyclonal Antibody -
Immunofluorescence analysis of A549 cells, using Stefin A Antibody. The picture on the right is blocked with the synthesized peptide. -
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using Stefin A Antibody. The picture on the right is blocked with the synthesized peptide.
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