cytochrome P450 family 26 subfamily A member 1(CYP26A1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues. Two alternatively spliced transcript variants of this gene, which encode the distinct isoforms, have been reported. [provided by RefSeq, Jul 2008],
Western Blot analysis of various cells using CYP26A1 Polyclonal Antibody diluted at 1:1000
Western Blot analysis of 293 cells using CYP26A1 Polyclonal Antibody diluted at 1:1000
Western blot analysis of lysates from HepG2, HeLa, and 293 cells, using Cytochrome P450 26A1 Antibody. The lane on the right is blocked with the synthesized peptide.