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ELK Biotechnology
SKU:ES2070
CTPS Rabbit Polyclonal Antibody
CTPS Rabbit Polyclonal Antibody
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$248.00 USD
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CTPS Rabbit Polyclonal Antibody
Overview
| Product name: | CTPS rabbit pAb |
| Alternative Names: | CTPS1; CTPS; CTP synthase 1; CTP synthetase 1; UTP--ammonia ligase 1 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human CTPS. AA range:60-109 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 67kD |
| GeneID(Human): | 1503 |
| Human Swiss-Prot No: | P17812 |
| Cellular localization: | Cytoplasm, cytosol . Mainly cytosolic but when active detected in long filamentous structures (PubMed:25223282). Co-localizes with TNK2 in the cytosolic filaments (By similarity). . |
| Background: | This gene encodes an enzyme responsible for the catalytic conversion of UTP (uridine triphosphate) to CTP (cytidine triphospate). This reaction is an important step in the biosynthesis of phospholipids and nucleic acids. Activity of this proten is important in the immune system, and loss of function of this gene has been associated with immunodeficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of various cells using CTPS Polyclonal Antibody diluted at 1:500 -
Western Blot analysis of HuvEc cells using CTPS Polyclonal Antibody diluted at 1:500 -
Immunohistochemical analysis of paraffin-embedded Human lung cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbe -
Immunohistochemistry analysis of CTPS antibody in
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