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ELK Biotechnology

SKU:ES2051

CRF-RII Rabbit Polyclonal Antibody

CRF-RII Rabbit Polyclonal Antibody

Regular price $248.00 USD
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CRF-RII Rabbit Polyclonal Antibody

Overview

Product name: IRE1α rabbit pAb
Alternative Names: ERN1; IRE1; Serine/threonine-protein kinase/endoribonuclease IRE1; Endoplasmic reticulum-to-nucleus signaling 1; Inositol-requiring protein 1; hIRE1p; Ire1-alpha; IRE1a
Applications: WB
Recommended Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: Purified recombinant fragment of human IRE1α (aa282-433) expressed in E. Coli.
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
GeneID(Human): 2081
Human Swiss-Prot No: O75460
Cellular localization: Endoplasmic reticulum membrane ; Single-pass type I membrane protein .
Background: The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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