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ELK Biotechnology
SKU:ES2049
c-Rel Rabbit Polyclonal Antibody
c-Rel Rabbit Polyclonal Antibody
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c-Rel Rabbit Polyclonal Antibody
Overview
| Product name: | c-Rel rabbit pAb |
| Alternative Names: | REL; Proto-oncogene c-Rel |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Rel. AA range:470-519 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 68kD |
| GeneID（Human）: | 5966 |
| Human Swiss-Prot No: | Q04864 |
| Cellular localization: | Nucleus . |
| Background: | This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014], |
| Species Reactivity: | Human;Rat;Mouse; |
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