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ELK Biotechnology
SKU:ES2042
CRABP-II Rabbit Polyclonal Antibody
CRABP-II Rabbit Polyclonal Antibody
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CRABP-II Rabbit Polyclonal Antibody
Overview
| Product name: | CRABP-II rabbit pAb |
| Alternative Names: | CRABP2; Cellular retinoic acid-binding protein 2; Cellular retinoic acid-binding protein II; CRABP-II |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human CRABP2. AA range:41-90 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 16kD |
| GeneID(Human): | 1382 |
| Human Swiss-Prot No: | P29373 |
| Cellular localization: | Cytoplasm. Endoplasmic reticulum. Nucleus. Upon ligand binding, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. |
| Background: | This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2010], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of various cells using CRABP-II Polyclonal Antibody -
Western blot analysis of lysates from HT-29 cells, using CRABP2 Antibody. The lane on the right is blocked with the synthesized peptide. -
Immunohistochemical analysis of paraffin-embedded human colon cancer. 1, Tris-EDTA,pH9.0 was used for antigen retrieval. 2 Antibody was diluted at 1:200(4° overnight.3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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