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ELK Biotechnology
SKU:ES2035
COX4 Rabbit Polyclonal Antibody
COX4 Rabbit Polyclonal Antibody
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COX4 Rabbit Polyclonal Antibody
Overview
| Product name: | COX4 rabbit pAb |
| Alternative Names: | COX4I1; COX4; Cytochrome c oxidase subunit 4 isoform 1; mitochondrial; Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1; COX IV-1 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human COX41. AA range:11-60 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 17kD |
| GeneID(Human): | 1327 |
| Human Swiss-Prot No: | P13073 |
| Cellular localization: | Mitochondrion inner membrane ; Single-pass membrane protein . |
| Background: | Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes |
| Species Reactivity: | Human;Rat;Mouse; |
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Western Blot analysis of various cells using COX4 Polyclonal Antibody -
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using COX41 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from A549 cells, using COX41 Antibody. The lane on the right is blocked with the synthesized peptide. -
Western blot analysis of 1) Hela, 2) 3T3, 3) Mouse Brain, 4) Rat Brain using COX4 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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