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ELK Biotechnology

SKU:ES2026

COL5A3 Rabbit Polyclonal Antibody

COL5A3 Rabbit Polyclonal Antibody

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COL5A3 Rabbit Polyclonal Antibody

Overview

Product name: COL5A3 rabbit pAb
Alternative Names: COL5A3; Collagen alpha-3(V) chain
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Collagen V alpha3. AA range:221-270
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 170kD
GeneID(Human): 50509
Human Swiss-Prot No: P25940
Cellular localization: Secreted, extracellular space, extracellular matrix .
Background: This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are thought to be responsible for the symptoms of a subset of patients with Ehlers-Danlos syndrome type III. Messages of several sizes can be detected in northern blots but sequence information cannot confirm the identity of the shorter messages. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Rat;Mouse;
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