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ELK Biotechnology

ES2024

COL4A6 Rabbit Polyclonal Antibody

COL4A6 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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COL4A6 Rabbit Polyclonal Antibody

Overview

Product name: COL4A6 rabbit pAb
Alternative Names: COL4A6; Collagen alpha-6(IV) chain
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Collagen IV alpha6. AA range:1201-1250
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 160kD
GeneID（Human）: 1288
Human Swiss-Prot No: Q14031
Cellular localization: Secreted, extracellular space, extracellular matrix, basement membrane.
Background: This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013],
Species Reactivity: Human;Rat;Mouse;
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