COL1A2 Rabbit Polyclonal Antibody

Name: COL1A2 Rabbit Polyclonal Antibody
Brand: ELK Biotechnology
SKU: ES2020
Price: 248.0 USD
Availability: InStock

$248.00 USD

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COL1A2 Rabbit Polyclonal Antibody

Overview

Product name:	COL1A2 rabbit pAb
Alternative Names:	COL1A2; Collagen alpha-2(I) chain; Alpha-2 type I collagen
Applications:	WB;IHC;IF;ELISA
Recommended Dilutions:	WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human Collagen I. AA range:1-50
Storage:	Rabbit
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	200kD
GeneID（Human）:	1278
Human Swiss-Prot No:	P08123
Cellular localization:	Secreted, extracellular space, extracellular matrix .
Background:	This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008],
Species Reactivity:	Human;Mouse;Rat

Immunofluorescence analysis of human-stomach tissue. 1,COL1A2 Polyclonal Antibody(red) was diluted at 1:200(4°C,overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300(room temperature, 50min).3, Picture B: DAPI(blue) 10min. Picture A:Target. Pi
Immunofluorescence analysis of human-stomach tissue. 1,COL1A2 Polyclonal Antibody(red) was diluted at 1:200(4°C,overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300(room temperature, 50min).3, Picture B: DAPI(blue) 10min. Picture A:Target. Pi
Immunofluorescence analysis of rat-lung tissue. 1,COL1A2 Polyclonal Antibody(red) was diluted at 1:200(4°C,overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300(room temperature, 50min).3, Picture B: DAPI(blue) 10min. Picture A:Target. Picture
Immunofluorescence analysis of rat-lung tissue. 1,COL1A2 Polyclonal Antibody(red) was diluted at 1:200(4°C,overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300(room temperature, 50min).3, Picture B: DAPI(blue) 10min. Picture A:Target. Picture

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COL1A2 Rabbit Polyclonal Antibody

COL1A2 Rabbit Polyclonal Antibody

Overview