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ELK Biotechnology

SKU:ES2003

CLK4 Rabbit Polyclonal Antibody

CLK4 Rabbit Polyclonal Antibody

Regular price $248.00 USD
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CLK4 Rabbit Polyclonal Antibody

Overview

Product name: CLK4 rabbit pAb
Alternative Names: CLK4; Dual specificity protein kinase CLK4; CDC-like kinase 4
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human CLK4. AA range:101-150
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 65kD
GeneID(Human): 57396
Human Swiss-Prot No: Q9HAZ1
Cellular localization: Nucleus .
Background: CDC like kinase 4(CLK4) Homo sapiens The protein encoded by this gene belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse
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