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ELK Biotechnology

ES1988

Claudin-4 Rabbit Polyclonal Antibody

Claudin-4 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Claudin-4 Rabbit Polyclonal Antibody

Overview

Product name: Claudin-4 rabbit pAb
Alternative Names: CLDN4; CPER; CPETR1; WBSCR8; Claudin-4; Clostridium perfringens enterotoxin receptor; CPE-R; CPE-receptor; Williams-Beuren syndrome chromosomal region 8 protein
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Claudin 4. AA range:160-209
Storage: -20°C/1 year
Storage: Rabbit
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 22kD
GeneID（Human）: 1364
Human Swiss-Prot No: O14493
Cellular localization: Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein . CLDN4 is required for tight junction localization in the kidney. .
Background: The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq, Sep 2013],
Species Reactivity: Human;Mouse;Rat
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