1
/
of
1
ELK Biotechnology
SKU:ES1935
CdcA3 Rabbit Polyclonal Antibody
CdcA3 Rabbit Polyclonal Antibody
Regular price
$248.00 USD
Regular price
Sale price
$248.00 USD
Unit price
/
per
Shipping calculated at checkout.
Couldn't load pickup availability
CdcA3 Rabbit Polyclonal Antibody
Overview
| Product name: | CdcA3 rabbit pAb |
| Alternative Names: | CDCA3; C8; GRCC8; TOME1; Cell division cycle-associated protein 3; Gene-rich cluster protein C8; Trigger of mitotic entry protein 1; TOME-1 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human CDCA3. AA range:219-268 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 28kD |
| GeneID(Human): | 83461 |
| Human Swiss-Prot No: | Q99618 |
| Cellular localization: | Cytoplasm, cytosol . |
| Background: | domain:The KEN box is required for the association with the APC/C-Cdh1 complex.,function:F-box-like protein which is required for entry into mitosis. Acts by participating to E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase.,pathway:Protein modification; protein ubiquitination.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,PTM:Ubiquitinated and degraded by the APC/C-Cdh1 complex.,subunit:Interacts with SKP1A. Part of a SCF (SKP1-cullin-F-box) protein ligase complex., |
| Species Reactivity: | Human;Mouse;Rat |
-
Western Blot analysis of various cells using CdcA3 Polyclonal Antibody -
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using CDCA3 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from HepG2 cells, using CDCA3 Antibody. The lane on the right is blocked with the synthesized peptide.
Share
