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ELK Biotechnology

ES1853

Caspase-2 Rabbit Polyclonal Antibody

Caspase-2 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Caspase-2 Rabbit Polyclonal Antibody

Overview

Product name: Caspase-2 rabbit pAb
Alternative Names: CASP2; ICH1; NEDD2; Caspase-2; CASP-2; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Caspase 2. AA range:123-172
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 51kD
GeneID（Human）: 835
Human Swiss-Prot No: P42575
Cellular localization: nucleus,cytoplasm,mitochondrion,cytosol,membrane,
Background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011],
Species Reactivity: Human;Rat;Mouse;
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