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ELK Biotechnology

SKU:ES1839

CARD 10 Rabbit Polyclonal Antibody

CARD 10 Rabbit Polyclonal Antibody

Regular price $248.00 USD
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CARD 10 Rabbit Polyclonal Antibody

Overview

Product name: CARD 10 rabbit pAb
Alternative Names: CARD10; CARMA3; Caspase recruitment domain-containing protein 10; CARD-containing MAGUK protein 3; Carma 3
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human CARD10. AA range:481-530
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 120kD
GeneID(Human): 29775
Human Swiss-Prot No: Q9BWT7
Cellular localization: Cytoplasm .
Background: The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM, Mar 2008],
Species Reactivity: Human;Mouse
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