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ELK Biotechnology
SKU:ES1817
CABC1 Rabbit Polyclonal Antibody
CABC1 Rabbit Polyclonal Antibody
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$248.00 USD
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CABC1 Rabbit Polyclonal Antibody
Overview
| Product name: | CABC1 rabbit pAb |
| Alternative Names: | ADCK3; CABC1; PP265; Chaperone activity of bc1 complex-like; mitochondrial; Chaperone-ABC1-like; aarF domain-containing protein kinase 3 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human ADCK3. AA range:301-350 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 50kD |
| GeneID(Human): | 56997 |
| Human Swiss-Prot No: | Q8NI60 |
| Cellular localization: | Mitochondrion . Membrane ; Single-pass membrane protein . |
| Background: | This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of various cells using CABC1 Polyclonal Antibody -
Western Blot analysis of COLO205 cells using CABC1 Polyclonal Antibody -
Western blot analysis of lysates from HepG2 and mouse muscle cells, using ADCK3 Antibody. The lane on the right is blocked with the synthesized peptide. -
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).
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