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ELK Biotechnology
SKU:ES1805
C/EBP ζ Rabbit Polyclonal Antibody
C/EBP ζ Rabbit Polyclonal Antibody
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$248.00 USD
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C/EBP ζ Rabbit Polyclonal Antibody
Overview
| Product name: | C/EBP ζ rabbit pAb |
| Alternative Names: | CEBPZ; CBF2; CCAAT/enhancer-binding protein zeta; CCAAT-box-binding transcription factor; CBF; CCAAT-binding factor |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human CEBPZ. AA range:1-50 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 120kD |
| GeneID(Human): | 10153 |
| Human Swiss-Prot No: | Q03701 |
| Cellular localization: | Nucleus. |
| Background: | This gene belongs to the CEBP family. The encoded protein plays a role in cellular response to environmental stimuli through a transcriptional process that involves heat shock factors, conserved DNA elements (heat shock elements or HSEs) and CCAAT boxes. The protein acts as a DNA-binding transcriptional activator and regulates the heat-shock protein 70 (HSP70) promoter in a CCAAT-dependent manner. The protein is also involved in cell growth and differentiation, particularly, hematopoietic differentiation. Methylation of the promoter of this gene or mutations within the gene may be correlated with occurance of acute myeloid leukemia (AML). [provided by RefSeq, Jun 2016], |
| Species Reactivity: | Human;Rat;Mouse; |
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Western Blot analysis of various cells using C/EBP ζ Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA). -
Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absor -
Western blot analysis of lysates from COLO cells, using CEBPZ Antibody. The lane on the right is blocked with the synthesized peptide.
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