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ELK Biotechnology

ES1791

BRMS-1 Rabbit Polyclonal Antibody

BRMS-1 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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BRMS-1 Rabbit Polyclonal Antibody

Overview

Product name: BRMS-1 rabbit pAb
Alternative Names: BRMS1; Breast cancer metastasis-suppressor 1
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human BRMS1. AA range:21-70
Storage: -20°C/1 year
Storage: Rabbit
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 28kD
GeneID（Human）: 25855
Human Swiss-Prot No: Q9HCU9
Cellular localization: Nucleus. Cytoplasm. Predominantly nuclear.
Background: This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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