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ELK Biotechnology
SKU:ES1772
Blk Rabbit Polyclonal Antibody
Blk Rabbit Polyclonal Antibody
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$248.00 USD
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Blk Rabbit Polyclonal Antibody
Overview
| Product name: | Blk rabbit pAb |
| Alternative Names: | BLK; Tyrosine-protein kinase Blk; B lymphocyte kinase; p55-Blk |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human BLK. AA range:456-505 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 58kD |
| GeneID(Human): | 640 |
| Human Swiss-Prot No: | P51451 |
| Cellular localization: | Cell membrane ; Lipid-anchor . Present and active in lipid rafts. Membrane location is required for the phosphorylation of CD79A and CD79B (By similarity). . |
| Background: | This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of various cells using Blk Polyclonal Antibody diluted at 1:500 -
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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