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ELK Biotechnology
SKU:ES1737
AVP Receptor V3 Rabbit Polyclonal Antibody
AVP Receptor V3 Rabbit Polyclonal Antibody
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AVP Receptor V3 Rabbit Polyclonal Antibody
Overview
| Product name: | AVP Receptor V3 rabbit pAb |
| Alternative Names: | AVPR1B; AVPR3; VPR3; Vasopressin V1b receptor; V1bR; AVPR V1b; AVPR V3; Antidiuretic hormone receptor 1b; Vasopressin V3 receptor |
| Applications: | WB;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human AVPR1B. AA range:275-324 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 47kD |
| GeneID(Human): | 553 |
| Human Swiss-Prot No: | P47901 |
| Cellular localization: | Cell membrane ; Multi-pass membrane protein . |
| Background: | The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Rat;Mouse; |
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Western Blot analysis of various cells using AVP Receptor V3 Polyclonal Antibody -
Western blot analysis of lysates from COLO and HepG2 cells, using AVPR1B Antibody. The lane on the right is blocked with the synthesized peptide. -
Western blot analysis of the lysates from HUVECcells using AVPR1B antibody.
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