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ELK Biotechnology
SKU:ES1660
ANT3 Rabbit Polyclonal Antibody
ANT3 Rabbit Polyclonal Antibody
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$248.00 USD
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ANT3 Rabbit Polyclonal Antibody
Overview
| Product name: | ANT3 rabbit pAb |
| Alternative Names: | SLC25A6; ANT3; CDABP0051; ADP/ATP translocase 3; ADP; ATP carrier protein 3; ADP,ATP carrier protein, isoform T2; ANT 2; Adenine nucleotide translocator 3; ANT 3; Solute carrier family 25 member 6 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human SLC25A6. AA range:121-170 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 32kD |
| GeneID(Human): | 293 |
| Human Swiss-Prot No: | P12236 |
| Cellular localization: | Mitochondrion inner membrane ; Multi-pass membrane protein . Membrane ; Multi-pass membrane protein . The complex formed with ARL2BP, ARL2 and SLC25A6/ANT3 is expressed in mitochondria (By similarity). May localize to non-mitochondrial membranes (By similarity). . |
| Background: | This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Jun 2013], |
| Species Reactivity: | Human;Rat;Mouse; |
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Western Blot analysis of various cells using ANT3 Polyclonal Antibody diluted at 1:2000 -
Western blot analysis of lysates from HepG2 and 293 cells, using SLC25A6 Antibody. The lane on the right is blocked with the synthesized peptide. -
Western blot analysis of the lysates from K562 cells using SLC25A6 antibody. -
Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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