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ELK Biotechnology

ES1640

Aldolase B Rabbit Polyclonal Antibody

Aldolase B Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Aldolase B Rabbit Polyclonal Antibody

Overview

Product name: Aldolase B rabbit pAb
Alternative Names: ALDOB; ALDB; Fructose-bisphosphate aldolase B; Liver-type aldolase
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human ALDOB. AA range:111-160
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 39kD
GeneID（Human）: 229
Human Swiss-Prot No: P05062
Cellular localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite .
Background: Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high
Species Reactivity: Human;Mouse;Rat
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