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ELK Biotechnology
SKU:ES1590
Actin α1 Rabbit Polyclonal Antibody
Actin α1 Rabbit Polyclonal Antibody
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$248.00 USD
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Actin α1 Rabbit Polyclonal Antibody
Overview
| Product name: | Actin α1 rabbit pAb |
| Alternative Names: | ACTA1; ACTA; Actin; alpha skeletal muscle; Alpha-actin-1 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Actin-alpha-1. AA range:1-50 |
| Storage: | -20°C/1 year |
| Storage: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 45kD |
| GeneID(Human): | 58 |
| Human Swiss-Prot No: | P68133 |
| Cellular localization: | Cytoplasm, cytoskeleton. |
| Background: | The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of various cells using Actin α1 Polyclonal Antibody diluted at 1:500 -
Western Blot analysis of HEPG2-UV cells using Actin α1 Polyclonal Antibody diluted at 1:500 -
Immunohistochemistry analysis of paraffin-embedded human muscle tissue, using Actin-alpha-1 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from rat muscle cells, using Actin-alpha-1 Antibody. The lane on the right is blocked with the synthesized peptide.
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