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ELK Biotechnology
SKU:ES1481
Syk (phospho Tyr525) Rabbit Polyclonal Antibody
Syk (phospho Tyr525) Rabbit Polyclonal Antibody
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Syk (phospho Tyr525) Rabbit Polyclonal Antibody
Overview
| Product name: | Syk (phospho Tyr525) rabbit pAb |
| Alternative Names: | SYK; Tyrosine-protein kinase SYK; Spleen tyrosine kinase; p72-Syk |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human SYK around the phosphorylation site of Tyr525. AA range:491-540 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 72kD |
| GeneID(Human): | 6850 |
| Human Swiss-Prot No: | P43405 |
| Cellular localization: | Cell membrane . Cytoplasm, cytosol . |
| Background: | This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010], |
| Species Reactivity: | Human;Mouse;Rat;Monkey |
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