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ELK Biotechnology
SKU:ES1446
Integrin β3 (phospho Tyr785) Rabbit Polyclonal Antibody
Integrin β3 (phospho Tyr785) Rabbit Polyclonal Antibody
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Integrin β3 (phospho Tyr785) Rabbit Polyclonal Antibody
Overview
| Product name: | Integrin β3 (phospho Tyr785) rabbit pAb |
| Alternative Names: | ITGB3; GP3A; Integrin beta-3; Platelet membrane glycoprotein IIIa; GPIIIa; CD antigen CD61 |
| Applications: | IF;ELISA;IHC |
| Recommended Dilutions: | IF/ICC 1:50-300; ELISA 1:2000-20000; IHC-p 1:50-200 |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Integrin beta3 around the phosphorylation site of Tyr785. AA range:739-788 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 87kD |
| GeneID(Human): | 3690 |
| Human Swiss-Prot No: | P05106 |
| Cellular localization: | Cell membrane ; Single-pass type I membrane protein . Cell projection, lamellipodium membrane . Cell junction, focal adhesion . Cell junction, synapse, postsynaptic cell membrane ; Single-pass type I membrane protein . Cell junction, synapse . |
| Background: | The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of various cells using Phospho-Integrin β3 (Y785) Polyclonal Antibody diluted at 1:500 -
Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using Integrin beta3 (Phospho-Tyr785) Antibody -
Western blot analysis of lysates from HeLa cells, HepG2 cells and HUVEC cells, using Integrin beta3 (Phospho-Tyr785) Antibody. The lane on the right is blocked with the phospho peptide. -
Immunohistochemical analysis of paraffin-embedded human spleen. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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