Tau (phospho Ser396) Rabbit Polyclonal Antibody

Name: Tau (phospho Ser396) Rabbit Polyclonal Antibody
Brand: ELK Biotechnology
SKU: ES1412
Price: 248.0 USD
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Tau (phospho Ser396) Rabbit Polyclonal Antibody

Overview

Product name:	Tau (phospho Ser396) rabbit pAb
Alternative Names:	MAPT; MAPTL; MTBT1; TAU; Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau
Applications:	IF;WB;IHC;ELISA
Recommended Dilutions:	IF: 1:50-200 WB 1:500-2000, IHC 1:50-300 IHC 1:50-300
Immunogen:	The antiserum was produced against synthesized peptide derived from human Tau around the phosphorylation site of Ser396. AA range:681-730
Storage:	Rabbit
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	50-85kD
GeneID（Human）:	4137
Human Swiss-Prot No:	P10636
Cellular localization:	Cytoplasm, cytosol . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cytoskeleton . Cell projection, axon . Cell projection, dendrite . Secreted . Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components (PubMed:10747907). Can be secreted; the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion (PubMed:32272059). .
Background:	This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008],
Species Reactivity:	Human;Mouse;Rat

Immunofluorescence analysis of A549. 1,primary Antibody(red) was diluted at 1:200(4°C overnight). 2, Goat Anti Rabbit IgG (H&L) - Alexa Fluor 594 Secondary antibody was diluted at 1:1000(room temperature, 50min).3, Picture B: DAPI(blue) 10min.
Immunofluorescence analysis of Hela cell. 1,Tau (phospho Ser396) Polyclonal Antibody(green) was diluted at 1:200(4° overnight). 2, Goat Anti Rabbit Alexa Fluor 488 Catalog:RS3211 was diluted at 1:1000(room temperature, 50min). 3 DAPI(blue) 10min.
Immunofluorescence analysis of human-lung tissue. 1,Tau (phospho Ser396) Polyclonal Antibody(red) was diluted at 1:200(4°C,overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300(room temperature, 50min).3, Picture B: DAPI(blue) 10min. Picture A
Immunofluorescence analysis of human-lung tissue. 1,Tau (phospho Ser396) Polyclonal Antibody(red) was diluted at 1:200(4°C,overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300(room temperature, 50min).3, Picture B: DAPI(blue) 10min. Picture A

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Tau (phospho Ser396) Rabbit Polyclonal Antibody

Tau (phospho Ser396) Rabbit Polyclonal Antibody

Overview