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ELK Biotechnology

ES1391

p73 (phospho Tyr99) Rabbit Polyclonal Antibody

p73 (phospho Tyr99) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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p73 (phospho Tyr99) Rabbit Polyclonal Antibody

Overview

Product name: p73 (phospho Tyr99) rabbit pAb
Alternative Names: TP73; P73; Tumor protein p73; p53-like transcription factor; p53-related protein
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human p73 around the phosphorylation site of Tyr99. AA range:66-115
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 73kD
GeneID（Human）: 7161
Human Swiss-Prot No: O15350
Cellular localization: Nucleus . Cytoplasm. Accumulates in the nucleus in response to DNA damage.
Background: tumor protein p73(TP73) Homo sapiens This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [provided by RefSeq, Feb 2011],
Species Reactivity: Human;Mouse
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