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ELK Biotechnology

ES1346

IκB-β (phospho Ser23) Rabbit Polyclonal Antibody

IκB-β (phospho Ser23) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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IκB-β (phospho Ser23) Rabbit Polyclonal Antibody

Overview

Product name: IκB-β (phospho Ser23) rabbit pAb
Alternative Names: NFKBIB; IKBB; TRIP9; NF-kappa-B inhibitor beta; NF-kappa-BIB; I-kappa-B-beta; IkB-B; IkB-beta; IkappaBbeta; Thyroid receptor-interacting protein 9; TR-interacting protein 9; TRIP-9
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human IkappaB-beta around the phosphorylation site of Ser23. AA range:8-57
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 37kD
GeneID（Human）: 4793
Human Swiss-Prot No: Q15653
Cellular localization: Cytoplasm . Nucleus .
Background: The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011],
Species Reactivity: Human;Mouse;Rat
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