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ELK Biotechnology

ES1316

FOXO4 (phospho Ser197) Rabbit Polyclonal Antibody

FOXO4 (phospho Ser197) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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FOXO4 (phospho Ser197) Rabbit Polyclonal Antibody

Overview

Product name: FoxO4 (phospho Ser197) rabbit pAb
Alternative Names: FOXO4; AFX; AFX1; MLLT7; Forkhead box protein O4; Fork head domain transcription factor AFX1
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human AFX around the phosphorylation site of Ser197. AA range:164-213
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 70kD
GeneID（Human）: 4303
Human Swiss-Prot No: P98177
Cellular localization: Cytoplasm. Nucleus. When phosphorylated, translocated from nucleus to cytoplasm. Dephosphorylation triggers nuclear translocation. Monoubiquitination increases nuclear localization. When deubiquitinated, translocated from nucleus to cytoplasm.
Background: This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010],
Species Reactivity: Human;Mouse
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