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ELK Biotechnology
SKU:ES1299
Dok-2 (phospho Tyr299) Rabbit Polyclonal Antibody
Dok-2 (phospho Tyr299) Rabbit Polyclonal Antibody
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$248.00 USD
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Dok-2 (phospho Tyr299) Rabbit Polyclonal Antibody
Overview
| Product name: | Dok-2 (phospho Tyr299) rabbit pAb |
| Alternative Names: | DOK2; Docking protein 2; Downstream of tyrosine kinase 2; p56(dok-2) |
| Applications: | WB;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human p56 Dok-2 around the phosphorylation site of Tyr299. AA range:266-315 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 48kD |
| GeneID(Human): | 9046 |
| Human Swiss-Prot No: | O60496 |
| Cellular localization: | cytosol, |
| Background: | docking protein 2(DOK2) Homo sapiens The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Monkey |
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Western Blot analysis of various cells using Phospho-Dok-2 (Y299) Polyclonal Antibody -
Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using p56 Dok-2 (Phospho-Tyr299) Antibody -
Western blot analysis of lysates from COS7 cells treated with insulin 0.01U/ml 15', Jurkat cells treated with insulin 0.01U/ml 15' and 293 cells treated with serum 20% 15', using p56 Dok-2 (Phospho-Tyr299) Antibody. The lane on the right is blocked with t
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