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ELK Biotechnology

ES1276

Calnexin (phospho Ser583) Rabbit Polyclonal Antibody

Calnexin (phospho Ser583) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Calnexin (phospho Ser583) Rabbit Polyclonal Antibody

Overview

Product name: Calnexin (phospho Ser583) rabbit pAb
Alternative Names: CANX; Calnexin; IP90; Major histocompatibility complex class I antigen-binding protein p88; p90
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Calnexin around the phosphorylation site of Ser583. AA range:543-592
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 90kD
GeneID（Human）: 821
Human Swiss-Prot No: P27824
Cellular localization: Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Endoplasmic reticulum . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545, PubMed:17081065). The palmitoylated form preferentially localizes to the perinuclear rough ER (PubMed:22314232). .
Background: This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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