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ELK Biotechnology

ES1124

NF-E4 (Acetyl Lys43) Rabbit Polyclonal Antibody

NF-E4 (Acetyl Lys43) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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NF-E4 (Acetyl Lys43) Rabbit Polyclonal Antibody

Overview

Product name: NF-E4 (Acetyl Lys43) rabbit pAb
Alternative Names: NFE4; Transcription factor NF-E4
Applications: WB;ELISA;IHC
Recommended Dilutions: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: Synthesized acetyl-peptide derived from the human NF-E4 around the acetylation site of K43.
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 19kD
GeneID（Human）: 58160
Human Swiss-Prot No: Q86UQ8
Cellular localization: Nucleus .
Background: The erythroid-specific protein encoded by this gene, and the ubiquitous transcription factor CP2, form the stage selector protein (SSP) complex, which is involved in preferential expression of the gamma-globin genes in fetal erythroid cells. Alternate use of an in-frame upstream non-AUG (CUG) translation initiation codon, and a downstream AUG codon, results in two isoforms. While the long isoform (22 kDa) acts as an activator, the short isoform (14 kDa) has been shown to repress gamma-globin gene expression. This gene is located in an intron of the FBXL13 gene on the opposite strand. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Rat;Mouse;
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