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ELK Biotechnology

ES1108

Ku-70 (Acetyl Lys542) Rabbit Polyclonal Antibody

Ku-70 (Acetyl Lys542) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Ku-70 (Acetyl Lys542) Rabbit Polyclonal Antibody

Overview

Product name: Ku-70 (Acetyl Lys542) rabbit pAb
Alternative Names: XRCC6; G22P1; X-ray repair cross-complementing protein 6; 5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit;CTC box-binding factor 75 kDa subunit; CTC75; CTCBF; DNA repair protein XRCC6; Lupus Ku autoantigen protein p70; Ku70; Thyroid-lupus autoantigen; TLAA; X-ray repair complementing defective repair in Chinese hamster cells 6
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Immunogen: Synthesized acetyl-peptide derived from the human Ku-70 around the acetylation site of K542.
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 100,70kD
GeneID（Human）: 2547
Human Swiss-Prot No: P12956
Cellular localization: Nucleus . Chromosome .
Background: The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Rat;Mouse;
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