1 1

ELK Biotechnology

ES1072

Cleaved-Plasma Kallikrein HC (R390) Rabbit Polyclonal Antibody

Cleaved-Plasma Kallikrein HC (R390) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
Sale Sold out
Shipping calculated at checkout.
Size

Cleaved-Plasma Kallikrein HC (R390) Rabbit Polyclonal Antibody

Overview

Product name: Cleaved-Plasma Kallikrein HC (R390) rabbit pAb
Alternative Names: KLKB1; KLK3; Plasma kallikrein; Fletcher factor; Kininogenin; Plasma prekallikrein
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human KLKB1. AA range:341-390
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 45kD
GeneID（Human）: 3818
Human Swiss-Prot No: P03952
Cellular localization: Secreted.
Background: This gene encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations in this gene cause prekallikrein deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],
Species Reactivity: Human;Rat;Mouse;
View full details