PCGF4, Polycomb complex protein BMI 1, RING finger protein 51, RNF51
Source:
Rabbit
Applications:
WB
Species:
Human
Recommended dilutions:
WB 1:1,000-2,000
Immunogen:
Recombinant Protein
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1mg/ml
Observed band:
37-43kDa
GeneID（Human）:
100532731
Human Swiss-Prot No:
P35226
Cellular localization:
Cytoplasm, Nucleus
Background:
Bmi1 is a component of the PRC1 complex, which together with Ring1 strongly enhances the E3 ubiquitin ligase activity of the Ring2 catalytic subunit . Bmi1 plays an important role in the regulation of cell proliferation and senescence through repression of the p16 INK4A and p19 ARF genes and is required for maintenance of adult hematopoietic and neural stem cells .
