KIAA0652, Apg13,Autophagy-related protein 13 antibody
Source:
Rabbit
Applications:
IHC
Species:
Human
Recommended dilutions:
IHC 1:100-200
Immunogen:
Recombinant Protein
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1mg/ml
Observed band:
57kDa
GeneID（Human）:
9776
Human Swiss-Prot No:
O75143
Cellular localization:
Cytoplasm
Background:
Atg13 was identified as a constitutively expressed protein that was genetically linked to Atg1/Apg1, a protein kinase required for autophagy. Overexpression of Atg1 suppresses the defects in autophagy observed in Atg13 mutants. Autophagy requires a direct association between Atg1 and Atg13, and is inhibited by TOR-dependent phosphorylation of Atg13 under high-nutrient conditions.
