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ELK Biotechnology
SKU:EA339
IkB α Rabbit Polyclonal Antibody
IkB α Rabbit Polyclonal Antibody
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$248.00 USD
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IkB α Rabbit Polyclonal Antibody
Overview
| Product name: | IkB α Rabbit pAb |
| Reactivity: | Human, Mouse, Rat |
| Alternative Names: | I kappa B alpha antibody, IkB-alpha antibody, IKBA antibody, MAD3 antibody, NFKB inhibitor antibody |
| Source: | Rabbit |
| Applications: | WB, IHC |
| Species: | Human |
| Recommended dilutions: | WB 1:500-1,000 IHC 1:100-200 |
| Immunogen: | Recombinant Protein |
| Storage: | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1mg/ml |
| Observed band: | 40kDa |
| GeneID(Human): | 4792 |
| Human Swiss-Prot No: | P25963 |
| Cellular localization: | Cytoplasm, Nucleus |
| Background: | Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. IκBα phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory cytokines, growth factors, and chemokines. |
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Immunohistochemical analysis of paraffin-embedded Rat Kidney Tissue using IkBα(EA339)Rabbit pAb diluted at 1:200. -
Immunohistochemical analysis of paraffin-embedded Human Stomach Tissue using IkBα(EA339)Rabbit pAb diluted at 1:200. -
Western blot analysis of 1) Hela Cell Lysate, 2)PC12 Cell Lysate, 3) 3T3 Cell Lysate using IkB α (EA339)Rabbit pAb diluted at 1:1000.
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