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ELK Biotechnology

SKU:EA339

IkB α Rabbit Polyclonal Antibody

IkB α Rabbit Polyclonal Antibody

Regular price $248.00 USD
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IkB α Rabbit Polyclonal Antibody

Overview

Product name: IkB α Rabbit pAb
Reactivity: Human, Mouse, Rat
Alternative Names: I kappa B alpha antibody, IkB-alpha antibody, IKBA antibody, MAD3 antibody, NFKB inhibitor antibody
Source: Rabbit
Applications: WB, IHC
Species: Human
Recommended dilutions: WB 1:500-1,000  IHC 1:100-200
Immunogen: Recombinant Protein
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Polyclonal
Isotype: IgG
Concentration: 1mg/ml
Observed band: 40kDa
GeneID(Human): 4792
Human Swiss-Prot No: P25963
Cellular localization: Cytoplasm, Nucleus
Background: Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. IκBα phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory cytokines, growth factors, and chemokines.
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