PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1mg/ml
Observed band:
75,80,90kDa
GeneID（Human）:
821
Human Swiss-Prot No:
P27824
Cellular localization:
Endoplasmic reticulum membrane,Melanosome.
Background:
Calnexin is a chaperone, characterized by assisting protein folding and quality control, ensuring that only properly folded and assembled proteins proceed further along the secretory pathway. Calnexin is a integral protein (that appears variously as a 90kDa, 80kDa or 75kDa band on western blotting depending on the source of the antibody) of the endoplasmic reticulum (ER). It consists of a large (50 kDa) N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic tail.
