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ELK Biotechnology
SKU:EM1269
Phospho-Akt (S473) (6F8) Mouse Monoclonal Antibody
Phospho-Akt (S473) (6F8) Mouse Monoclonal Antibody
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$248.00 USD
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Phospho-Akt (S473) (6F8) Mouse Monoclonal Antibody
Overview
| Product name: | Phospho-Akt (S473) (6F8) Mouse mAb |
| Reactivity: | Human |
| Alternative Names: | c Akt antibody, MGC9965 antibody, Protein kinase B antibody, RAC antibody, PRKBA antibody |
| Source: | Mouse |
| Applications: | WB, IHC |
| Species: | Human |
| Recommended dilutions: | WB 1:1,000-2,000 IHC 1:100-200 |
| Immunogen: | Synthetic Peptide |
| Storage: | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality: | Monoclonal |
| Isotype: | IgG1 |
| Concentration: | 1mg/ml |
| Observed band: | 60kDa |
| GeneID(Human): | 207 |
| Human Swiss-Prot No: | P31749 |
| Cellular localization: | Cytoplasm,Nucleus,Cell membrane |
| Background: | Akt, is a serine/threonine-specific protein kinase that plays a key role in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription and cell migration. Akt1 is involved in cellular survival pathways, by inhibiting apoptotic processes. Akt1 is also able to induce protein synthesis pathways, and is therefore a key signaling protein in the cellular pathways that lead to skeletal muscle hypertrophy, and general tissue growth. |
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Western blot analysis of PC3 Cell Lysateusing Phospho-Akt Ser473(EM1269)Mouse mAb diluted at 1:1000. -
Immunohistochemical analysis of paraffin-embedded Human Lung Carcinoma Tissue using Phospho-Akt Ser473(EM1269)Mouse mAb diluted at 1:200. -
Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma Tissue using Phospho-Akt Ser473(EM1269)Mouse mAb diluted at 1:200.
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