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Dima Biotech

PME100998

Human PRAME Protein, hFc Tag

Human PRAME Protein, hFc Tag

$411.00 USD
$411.00 USD
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Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

CT130;MAPE;OIP-4;OIP4
DESCRIPTION

Recombinant human PRAME protein with C-terminal human Fc tag
DELIVERY

Under development
UNIPROT ID

P78395
EXPRESSION HOST

HEK293
TAG

C-Human Fc Tag
MOLECULAR CHARACTERIZATION

PRAME (Met1-Asn509) hFc (Glu99-Ala330)
MOLECULAR WEIGHT

The protein has a predicted molecular mass of 81.51 kDa after removal of the signal peptide.
PURITY

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
BACKGROUND

This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
USAGE

Research use only
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